The research group led by Yang Na from the Medical College of Nankai University and the National Key Laboratory of Medicinal Chemistry and Biology, together with the research group led by Xu Ruiming and Fan Qusen from the Institute of Biophysics of the Chinese Academy of Sciences, conducted a study that revealed that the MLL1-AF10 fusion protein passes the OM-LZ domain of AF10 and the Coiled-Coil domain of the uncatalyzed DOT1L domain, then forms oligomers.